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From Human Salivary Proteome Wiki
Term Data- Source Ontology
- Gene Ontology
- Accession
- GO:0002102
- Term Name
- podosome
- RO 0002161
- http://purl.obolibrary.org/obo/NCBITaxon_4751
- Reviewer's Comment
- Note that podosomes can be distinguished from other F-actin-rich structures or from other matrix contacts. For example, focal adhesions and focal contacts do not display a core structure of F-actin. Unlike focal adhesions, podosome assembly does not require de novo protein synthesis. However, most of the podosome ring components are found in focal adhesions and other cell-matrix contacts. Podosomes are typically found in cells that cross tissue boundaries, recruited to the leading edge of migrating cells, and are often sites of extracellular matrix degradation.
- Database Cross Reference
- Wikipedia:Podosome
- Definition
- An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.
- Has Obo Namespace
- cellular_component
- Id
- GO:0002102
- Link
- http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&query=GO:0002102
- Usage
- Search for pages annotated with this term
Term Relationship
Parents (1)
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Siblings (20)
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HSPW Version 1.5.3.
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