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Term Data

Source Ontology
Gene Ontology
Accession
GO:0002102
Term Name
podosome
RO 0002161
http://purl.obolibrary.org/obo/NCBITaxon_4751
Reviewer's Comment
Note that podosomes can be distinguished from other F-actin-rich structures or from other matrix contacts. For example, focal adhesions and focal contacts do not display a core structure of F-actin. Unlike focal adhesions, podosome assembly does not require de novo protein synthesis. However, most of the podosome ring components are found in focal adhesions and other cell-matrix contacts. Podosomes are typically found in cells that cross tissue boundaries, recruited to the leading edge of migrating cells, and are often sites of extracellular matrix degradation.
Database Cross Reference
Wikipedia:Podosome
Definition
An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.
Has Obo Namespace
cellular_component
Id
GO:0002102
Link
http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&query=GO:0002102
Usage
Search for pages annotated with this term

Term Relationship

Parents (1) Siblings (20)
Ontology Search
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